Table 2.
Demographic and Clinical Characteristics of the Non-Interventional Study Population
| Characteristic | Non-Diabetic (n = 10) Mean ± SEM | 95% CI | PDR (n = 17) Mean ± SEM | 95% CI | P |
|---|---|---|---|---|---|
| Age (y) | 44.8 ± 6.5 | 30.1–59.5 | 55.4 ± 2.5 | 50.0–60.8 | 0.08a |
| BMI (kg/m2) | 27.5 ± 2.1 | 22.3–32.7 | 25.6 ± 0.9 | 23.7–27.6 | 0.36a |
| DM2 (y) | — | — | 15.4 ± 1.9 | 11.4–19.4 | — |
| HbA1c (%) | 4.7 ± 0.7 | 2.9–6.4 | 7.9 ± 0.7 | 6.5–9.4 | 0.009a |
| SCr (mg/dL) | 0.9 ± 0.06 | 0.7–1.0 | 1.5 ± 0.2 | 1.1–1.9 | 0.01a |
| eGFR (mL/min) | 103.5 ± 9.9 | 81.0–126.0 | 64.4 ± 8.1 | 47.2–81.6 | 0.006a |
| SPRL (ng/mL) | 8.6 ± 1.3 | 5.6–11.6 | 8.5 ± 0.9 | 6.5–10.5 | 0.94a |
| VPRL (ng/mL) | 1.8 ± 1.0 | –1.0 to 4.7 | 1.2 ± 0.09 | 1.0–1.4 | 0.32a |
Non-diabetic patients underwent vitrectomy due to rhegmatogenous retinal detachment or epiretinal membrane. Patients with PDR underwent vitrectomy due to vitreous hemorrhage and/or retinal detachment. P values compare non-diabetic and PDR groups. eGFR, glomerular filtration rate (CKD-EPI equation); VPRL, vitreous PRL.
a
Based on Student's t-test.