Table 2.
Ocular Characteristics of Patients Included in the Study
| Group 1 (NIH 0) | Group 2 (NIH 1) | Group 3 (NIH 2) | Group 4 (NIH 3) | |
|---|---|---|---|---|
| Diagnostic Criteria | n = 14 | n = 9 | n = 16 | n = 10 |
| Oxford Score | ||||
| Mean ± SD | 0.1 ± 0.4 | 1.4 ± 0.5 | 3.2 ± 1.2 | 4 ± 0.7 |
| Range | 0–1 | 1–2 | 1–5 | 3–5 |
| Sign. vs. NIH 0 | P > 0.05 | P < 0.0001 | P < 0.0001 | |
| Schirmer Test I (mm) | ||||
| Mean ± SD | 19.3 ± 8.9 | 8.9 ± 8.3 | 2.8 ± 3.6 | 2.3 ± 2.9 |
| Range | 7–35 | 2–25 | 0–11 | 0–10 |
| Sign. vs. NIH 0 | P < 0.05 | P < 0.0001 | P < 0.0001 | |
| TBUT, s | ||||
| Mean ± SD | 4.2 ± 2.3 | 2.9 ± 1.6 | 2.1 ± 0.8 | 1.9 ± 0.6 |
| Range | 2–10 | 1–6 | 1–3 | 1–3 |
| Sign. vs. NIH 0 | P > 0.05 | P < 0.01 | P < 0.01 | |
| OSDI score | ||||
| Mean ± SD | 6.5 ± 5.6 | 19.8 ± 12.4 | 37.8 ± 17.4 | 67.1 ± 12.8 |
| Range | 0–20.8 | 10.4–43.8 | 11.4–68.2 | 43.2–81.8 |
| Sign. vs. NIH 0 | P < 0.05 | P < 0.0001 | P < 0.0001 |
When data were normally distributed, significant difference (sign.) was tested using one-way ANOVA with Tukey's post hoc test; when data were not normally distributed Kruskal-Wallis test was used.