Table 2.
Meta-analysis of laboratory findings between severe and non-severe patients with COVID-19.
Parameters | No. of cohort | Sample size (Severe/Non-Severe) | SMD | 95% CI | I2 (%) | Statistical method | p | Publication bias (p Egger) |
---|---|---|---|---|---|---|---|---|
Leukocyte (×109/L) | 24 | 1119/2825 | 0.35 | 0.09 to 0.61 | 90 | REM | 0.009* | 0.725 |
Lymphocyte (×109/L) | 24 | 1090/2832 | −0.57 | −0.73 to −0.40 | 73 | REM | <0.00001* | 0.547 |
Neutrophil (×109/L) | 16 | 675/1257 | 0.50 | 0.28 to 0.72 | 72 | REM | <0.0001* | 0.892 |
Thrombocyte (×109/L) | 15 | 624/2103 | −0.33 | −0.52 to −0.14 | 67 | REM | 0.0006* | 0.840 |
D-dimer (μg/mL or mg/L) | 14 | 451/1205 | 0.56 | 0.32 to 0.80 | 74 | REM | <0.00001* | 0.865 |
CRP (mg/L) | 17 | 737/1272 | 0.99 | 0.69 to 1.29 | 85 | REM | <0.00001* | 0.112 |
PCT (ng/mL) | 13 | 596/1041 | 0.19 | −0.06 to 0.44 | 75 | REM | 0.14 | 0.930 |
SMD, standard mean difference; CI, confidence interval, FEM, fixed-effect model; REM, random-effect model.
p < 0.05.