Table E3.

Identification of viral susceptibility risk factors

Variable considered	Univariate				Multivariate
	OR	95% CI lower bound	95% CI upper bound	Unadjusted P value	OR	95% CI lower bound	95% CI upper bound	Adjusted P value
Age	0.991	0.981	1.00	.0907	0.727	0.982	1.01	.388
IgM∗	0.626	0.397	0.937	.0325	0.612	0.394	0.900	.019
IgA∗	0.733	0.585	0.893	.0038	0.854	0.680	1.05	.152
Regular child contact	2.04	1.446	2.89	.0000486	2.16	1.45	3.22	.000158
On antibiotic prophylaxis	0.813	0.603	1.10	.174	0.676	0.451	1.01	.0558
CD3+CD4+ count <400	1.08	0.783	1.48	.645	0.852	0.581	1.24	.408
Bronchiectasis	1.46	1.052	2.03	.023	1.76	1.20	2.59	.00384

OR, Odds ratio.

IgG was excluded from analysis because clinical practice allows adjustment of trough dose on the basis of clinical symptoms.

Bold indicates statistical significance (P < .05).

^∗Continuous variables.