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. 2020 Aug 21;3(11):e201900630. doi: 10.26508/lsa.201900630

Figure S5. XL-MS of Pch2–(ORC) origin recognition complex.

Figure S5.

(A) Table indicating inter-ORC and intra-ORC cross-linked peptides (nonredundant (inter- and intramolecular) cross-links with a false discovery rate of 2%). (B) Schematic indicating identified inter/intra-ORC nonredundant cross-links. Blue: inter-ORC, red: intra-ORC. (C) Schematic indicating Pch2–Pch2 cross-links. Note that we classified the Pch2–Pch2 cross-links as intramolecular (see text for further details). NTD, NH2-terminal domain; AAA+, AAA+ ATPase domain. (D) Schematic indicating identified nonredundant intermolecular cross-links between the NTD of Pch2 and the ORC. (E) Schematic of nonredundant intermolecular cross-links between the AAA+ ATPase domain of Pch2 with the ORC. Network plots were generated using xVis website (https://xvis.genzentrum.lmu.de).