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Pharmacokinetic parameters of bismuth after a single oral dose of Wei Bi Mei (mean ± SD, n = 7).
| Parameter | C max (ng/mL) | t max (h) | t 1/2 (h) | V d (×103 L) | AUC0–24 (h ng/mL) | AUC0-∞ (h ng/mL) | MRT (0-t) (h) |
|---|---|---|---|---|---|---|---|
| 0.85 ± 0.55 | 2.29 ± 0.76 | 9.98 ± 5.13 | 196.47 ± 98.79 | 8.33 ± 5.42 | 8.43 ± 5.08 | 11.82 ± 6.78 |
C max, peak concentration; tmax, time to peak concentration; t1/2, half-life; Vd, volume of distribution; AUC, area under the curve; MRT, mean residence time.
