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Pharmacokinetic parameters of bismuth following multiple-dose Wei Bi Mei administration (mean ± SD, n = 7).
| Parameter | C max (ng/mL) | t max (d) | t 1/2 (d) | V d (×103 L) | AUC0-t (d ng/mL) | AUC0-∞ (d ng/mL) | MRT (0-t) (d) |
|---|---|---|---|---|---|---|---|
| 2.25 ± 1.18 | 2.0 | 20.04 ± 10.65 | 22.97 ± 9.82 | 55.26 ± 32.01 | 58.68 ± 36.64 | 21.69 ± 3.95 |
C max, peak concentration; tmax, time to peak concentration; t1/2, half-life; Vd, volume of distribution; AUC, area under the curve; MRT, mean residence time.
