Figure 1.

TCDD and Aroclor1254 coexposure promoted the formation of atherosclerotic lesions. Lesions of the aortic valve lipids in the (a) control and (b) TCDD+Aroclor1254 groups were visualized by Oil Red O staining (representative cross sections, magnification ×40). (c) Values are the means of the atherosclerotic lesion from individual mouse. (d) Effect of TCDD and Aroclor1254 coexposure on the mRNA expression of genes regulating atherogenesis in ApoE^−/− mice by RT-PCR. Data are expressed as means ± SEM (n = 6). ∗p < 0.05 and ∗∗∗p < 0.001, when compared between different groups.