Table 3.

Subgroup Analyses Between Fok I/rs2228570 Gene Polymorphism and Allergic Rhinitis

Variables	rs2228570 (Case/Control)			AA versus GG		AA versus GA		AA/GA versus GG		AA versus GA/GG		A versus G
	GG	GA	AA	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Gender
Male	84/112	74/81	40/18	2.96(1.59–5.53)	<0.001	1.53(1.28–4.61)	0.006	1.54(1.04–2.27)	0.031	2.71(1.50–4.92)	0.001	1.66(1.24–2.23)	0.001
Female	83/104	73/69	46/16	3.60(1.90–6.82)	<0.001	2.72(1.41–5.24)	0.002	1.75(1.17–2.62)	0.006	3.19(1.73–5.86)	<0.001	1.92(1.42–2.60)	<0.001
Age (years)
<60	91/128	93/96	59/23	3.61(2.08–6.26)	<0.001	2.65(1.51–4.64)	0.001	1.80(1.25–2.58)	0.001	3.12(1.86–5.25)	<0.001	1.38(1.05–1.82)	0.019
≥60	76/88	54/54	27/11	2.84(1.32–6.11)	0.006	2.45(1.11–5.44)	0.025	1.44(0.92–2.26)	0.108	2.68(1.28–5.62)	0.007	1.59(1.12–2.25)	0.009
Smoking
Yes	51/92	45/47	35/18	3.51(1.81–6.81)	<0.001	1.90(0.95–3.82)	0.068	2.22(1.38–3.56)	0.001	2.82(1.51–5.26)	0.001	2.08(1.47–2.96)	<0.001
No	116/124	102/103	51/16	3.41(1.84–6.31)	<0.001	3.22(1.72–6.01)	<0.001	1.37(0.97–1.95)	0.073	3.32(1.84–6.00)	<0.001	1.59(1.22–2.07)	0.001
Drinking
Yes	48/66	48/44	23/16	4.41(2.48–7.85)	<0.001	3.75(2.07–6.77)	<0.001	1.65(1.18–2.30)	0.003	4.11(2.36–7.15)	<0.001	1.91(1.48–2.46)	<0.001
No	119/150	99/106	63/18	1.98(0.94–4.14)	0.068	1.32(0.62–2.81)	0.475	1.63(0.98–2.70)	0.059	1.65(0.82–3.30)	0.156	1.51(1.04–2.20)	0.030
BMI
≥24	70/78	63/61	31/14	2.47(1.21–5.01)	0.011	2.14(1.04–4.42)	0.037	1.40(0.90–2.17)	0.139	2.31(1.18–4.54)	0.013	1.50(1.08–2.09)	0.016
<24	97/138	84/89	55/20	1.94(2.20–6.95)	<0.001	1.66(1.61–5.27)	<0.001	1.81(1.26–2.60)	0.001	3.45(1.99–5.96)	<0.001	1.97(1.50–2.59)	<0.001
Asthma
Yes	53/8	54/5	25/5	0.75(0.22–2.54)	0.649	0.46(0.12–1.75)	0.247	1.19(0.44–3.22)	0.728	0.61(0.20–1.86)	0.379	0.91(0.45–1.85)	0.793
No	114/208	93/145	61/29	3.84(2.33–6.31)	<0.001	3.28(1.96–5.48)	<0.001	1.61(1.18–2.2)	0.003	3.59(2.23–5.76)	<0.001	1.85(1.46–2.34)	<0.001