Table 5.
Univariate and multivariate logistic regression analysis to determine impaired GFR among patients with T2DM.
| Factors | Univariate analysis | Multivariate logistic regression analysis | ||
|---|---|---|---|---|
| Odd ratio (95% CI) | P value | Odd ratio (95% CI) | P value | |
| Female | 1.15 (1.09, 1.20) | <0.001 | 0.86 (0.51, 1.45) | 0.564 |
| Age (years) | 1.09 (1.08, 1.09) | <0.001 | 1.09 (1.07, 1.12) | <0.001 |
| BMI (kg/m2) | 0.95 (0.94, 0.95) | <0.001 | 0.98 (0.93, 1.02) | 0.326 |
| Smoking (yes) | 0.90 (0.84, 0.96) | 0.002 | 1.01 (0.51, 1.99) | 0.987 |
| Systolic BP (mmHg) | 1.02 (1.02, 1.02) | <0.001 | 1.02 (1.00, 1.04) | 0.030 |
| Diastolic BP (mmHg) | 0.97 (0.96, 0.97) | <0.001 | 0.98 (0.96, 1.01) | 0.311 |
| HemoglobinA1C (%) | 0.98 (0.97, 0.99) | 0.001 | 1.16 (1.04, 1.31) | 0.009 |
| Hemoglobin (g/dL) | 0.69 (0.68, 0.71) | <0.001 | 0.85 (0.74, 0.98) | 0.029 |
| Serum uric acid (mg/dL) | 1.42 (1.38, 1.46) | <0.001 | 1.90 (1.64, 2.20) | <0.001 |
| Total cholesterol (mg/dL) | 1.01 (1.01, 1.02) | <0.001 | 1.00 (0.99, 1.01) | 0.966 |
| Triglycerides (mg/dL) | 1.01 (1.01, 1.02) | <0.001 | 1.01 (0.99, 1.02) | 0.144 |
| HDL-cholesterol (mg/dL) | 0.99 (0.98, 0.99) | <0.001 | 1.00 (0.99, 1.01) | 1.000 |
| UACR (mg/gCr) | 1.01 (1.01, 1.02) | <0.001 | 1.01 (1.01, 1.02) | 0.045 |
Abbreviation: BP: blood pressure; BMI: body mass index; UACR: urine albumin creatinine ratio.
aAdjusted by age, sex, BMI, waist circumference, smoking, systolic BP, diastolic BP, HA1C, hemoglobin, serum uric acid, triglycerides, HDL-cholesterol, and albuminuria.