Table 5. Observed and expected frequencies of CYP2E1 (rs3813865) genotypes.

Population	Geno	N	Observed frequency percentage (CI)	Expected frequency percentage by HW law	Chi Squared	P value
Pakistani	585
	GG	424	72.47 [68.85–76.09]	71.01	7.08	<0.05
	GC	138	23.58 [20.14–27.02]	26.49
	CC	23	3.93 [2.36–5.50]	2.47
Punjabi	219
	GG	139	63.47 [57.09–69.85]	62.76	0.40	>0.05
	GC	69	31.50 [25.35–37.65]	32.91
	CC	11	5.02 [2.13–7.91]	4.31
Pathan	109
	GG	83	76.14 [68.14–84.14]	75.15	0.79	>0.05
	GC	23	21.10 [13.44–28.76]	23.06
	CC	3	2.75 [0–5.82]	1.77
Urdu	77
	GG	52	67.53 [54.8–80.26]	65.88	0.89	>0.05
	GC	21	27.27 [15.17–39.37]	30.56
	CC	4	5.19 [0–11.22]	3.54
Seraiki	64
	GG	46	71.87 [60.85–82.89]	72.51	0.16	>0.05
	GC	17	26.56 [15.74–37.38]	25.27
	CC	1	1.56 (0-4.6)	2.20
Balochi	61
	GG	51	83.60 [74.31–92.89]	78.36	16.23	<0.05
	GC	6	9.83 [2.36–17.3]	20.30
	CC	4	6.55 [0.34–12.76]	1.31
Sindhi	55
	GG	53	96.36 [91.41–100]	96.39	0.02	>0.05
	GC	2	3.63 [0–8.57]	3.56
	CC	0	0	0.03