Table 4.
Univariate and Multivariate Linear Regression Analyses Among Various Clinical Factors and Peripapillary Retinal Nerve Fiber Layer Thicknesses
| Univariate Regression | Multivariate Regression | |||
|---|---|---|---|---|
| Variable | β ± SE | P | β ± SE | P |
| Age | –0.256 ± 0.051 | <0.001 | –0.255 ± 0.058 | <0.001 |
| Sex (0 = male, 1 = female) | –0.471 ± 1.203 | 0.696 | ||
| Diabetes mellitus | –3.334 ± 1.171 | 0.005 | –3.370 ± 1.209 | 0.006 |
| Duration of diabetes | –0.599 ± 0.127 | <0.001 | ||
| HbA1c | –2.257 ± 0.809 | 0.006 | –0.912 ± 0.684 | 0.184 |
| Hypertension | –7.199 ± 1.400 | <0.001 | –4.087 ± 1.413 | 0.004 |
| BCVA | –18.046 ± 6.883 | 0.009 | –8.902 ± 7.035 | 0.207 |
| Intraocular pressure | –0.271 ± 0.103 | 0.102 | ||
| Spherical equivalent | 0.481 ± 0.237 | 0.043 | ||
| Axial length | –1.345 ± 0.466 | 0.004 | –2.029 ± 0.436 | <0.001 |
| Central foveal thickness | –0.007 ± 0.027 | 0.787 | ||
| Cup/disc ratio | –13.082 ± 4.350 | 0.003 | –7.106 ± 4.070 | 0.082 |
Boldface numbers indicate statistically significant differences at P < 0.05. Duration of diabetes and spherical equivalent were not included in the multivariate regression model because of the interaction between diabetes mellitus and axial length. SE, standard error.