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editorial
. 2020 Aug 7;9(9):15. doi: 10.1167/tvst.9.9.15

Table.

Example Treatment Parameters for Various Laser Modes and Settings and Effects on Therapeutic (Clinical Safety) Ranges

Laser Wavelength Retinal Power Duty Spot Duration Therapeutic
Mode (nm) Spot (um) (Watts) Cycle (%) (Seconds) Rangeg (Watts)
Nanoa 532 400 ∼24(mJ)d CW 3 × 10−9 0
Microb 532 100 ∼ 0.117d CW 0.00002 0.010
MP8 c,e 577 105 0.250 5 0.20 0.29
MP6 c,e 810 210 1.4 5 0.15 4h
MP c,e,f 810 525 1.7 5 0.30 15h

aNanosecond continuous wave (CW).

bMicrosecond CW.

cMicropulsed.

dEstimate, by titration.

eFixed, published.

fFixed, currently preferred; used in over 20,000 consecutive panmacular treatments (Luttrull, unpublished data 2020).

gCalculated difference between the laser power at given laser parameters required for reaching the activation threshold of 1.0 for the Arrhenius integrals of the therapeutic reset effect (lower limit of TR) and the 50/50 risk of thermal cell death (upper limit of TR).

hNote that the TR of these 810nm laser parameters exceed the maximum available power of current retinal lasers allowing use in all eyes of all patients for all indications, safely and effectively.