Table 2.
Multivariate Cox′s proportional hazards model analysis of disease-free survival and overall survival.
Variables | Overall survival | Disease-free survival | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Tumor size (cm) | 0.013* | 0.006** | ||
≤4 (ref) | 1 | 1 | ||
>4 | 3.327 (1.284–8.621) | 3.241 (1.398–7.509) | ||
LVSI | 0.005** | 0.003** | ||
Negative (ref) | 1 | 1 | ||
Positive | 3.807 (1.495–9.695) | 3.805 (1.590–9.104) | ||
LNM | 0.025* | 0.016* | ||
Negative (ref) | 1 | 1 | ||
Positive | 2.812 (1.136–6.959) | 2.764 (1.205–6.340) | ||
PTPRM | 0.038* | 0.018* | ||
Low (ref) | 1 | 1 | ||
High | 2.517 (1.091–21.439) | 4.403 (1.286–15.075) |
HR hazard ratio, CI confidence interval, LNM lymph node metastasis, LVSI lymphovascular space invasion, ref reference.
For the stepwise multivariate analysis, forward LR method was used to select significant variables. Variables entered for multivariate analysis were the following: tumor size, FIGO stage, LNM, LVSI, PTPRM. *P < 0.05, **P < 0.01, ***P < 0.001.