Fig. 6.

Electrocardiograph of Premature Junction Contractions in Carfentanil-Exposed Ferrets. Telemetered male ferrets were exposed to aerosolized carfentanil for 20 min, during which time cardiac parameters were recorded. We observed cardiac abnormalities in the pressure traces (pink) and electrocardiograph (green) in animals exposed to carfentanil. Premature junction contractions (PJCs) (circled in red) were seen throughout exposure timeframe. The PJCs were present in all exposed animals, and their appearance during times of respiratory depression indicates that they are most likely linked hypoxic conditions.