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. 2019 Nov 29;189(4):305–313. doi: 10.1093/aje/kwz262

Table 1.

Characteristics of Cases of Cognitive Declinea (First Decile of Slope or Lower) and Controls (Greater Than Median Slope) in the Nurses’ Health Study, United States, 1986b

Characteristic Cases
(n = 1,496)
Controls
(n = 7,478)
Mean (SD) % Mean (SD) %
Response to the 1986 questionnaireb 95.9 95.8
Age, years 61.3 (2.5) 60.9 (2.4)
Educational level
 Registered nurse 78.3 77.0
 Bachelor’s degree 16.1 16.9
 Master’s or doctoral degree 5.6 6.1
Current smokerc 19.7 15.8
History of chronic disease
 High blood pressure 38.7 31.3
 High cholesterol level 19.5 17.2
 Diabetes mellitus 4.9 2.8
Body mass indexc,d 25.9 (4.8) 25.3 (4.2)
Body mass index categoryc
 Underweight (<18.5) 1.4 0.9
 Normal-weight (18.5–24.9) 48.9 54.7
 Overweight (25.0–29.9) 32.8 31.7
 Obese (≥30.0) 16.9 12.8
Physical activity, MET-hours/week
 Total 13.1 (25.2) 13.6 (18.3)
 Low-intensitye 6.7 (9.2) 7.4 (9.6)
A-MeDi scorec 4.3 (1.8) 4.4 (1.9)
A-MeDi componentsc
 Food consumption, servings/day
  Vegetables 3.3 (1.9) 3.3 (1.9)
  Legumes 0.4 (0.3) 0.4 (0.3)
  Fruits 2.6 (1.5) 2.6 (1.5)
  Nuts 0.4 (0.5) 0.4 (0.5)
  Whole grains 1.6 (1.2) 1.6 (1.2)
  Fish 0.4 (0.3) 0.4 (0.3)
  Red/processed meat 0.8 (0.5) 0.8 (0.5)
 Alcohol consumption, g/day 6.3 (11.3) 6.5 (10.7)
 MUFA:SFA ratio 1.1 (0.2) 1.1 (0.2)

Abbreviations: A-MeDi, alternate Mediterranean diet; MET, metabolic equivalent of task; MUFA, monounsaturated fatty acid; SD, standard deviation; SFA, saturated fatty acid.

a Cognitive decline was measured using the Telephone Interview for Cognitive Status (25).

b The midpoint time of the longest study period for exposures (i.e., 1986 for body mass index).

c Among nonmissing values. Data were missing for 0.3% of cases and 0.1% of controls for smoking, 15.8% of cases and 12.0% of controls for body mass index, and 20.7% of cases and 18.3% of controls for A-MeDi score.

d Weight (kg)/height (m)2.

e Low-intensity physical activity was calculated as the sum of walking and stair-climbing.