Table 1.
Data on diarrhea in patients with COVID-19.
| First author | Study country | Hospital | N of patients | Diarrhea n (%) |
Diarrhea duration | Evacuations per day | State of patients | Nucleic acid tests in feces | Prognoses |
|---|---|---|---|---|---|---|---|---|---|
| Guan [11] | China | 552 hospitals | 1099 | 42(3.8%) | NA | NA | 5.0% were admitted to the ICU, 2.3% underwent invasive mechanical ventilation. | NA | 1.4% died. |
| Chen [12] | China | Jing yintan hospital | 99 | 2(2%) | NA | NA | NA | NA | 11 (11%) patients died of multiple organ failure |
| Huang [13] | China | Jing yintan hospital | 41 | 1(2.4%) | NA | NA | Dyspnoea in 22 (55%) of 40 patients | NA | Six (15%) died |
| Fang [14] | China | Wuhan tongji hospital | 305 | 146(49.5%) | (4.1 ± 2.5) d, 3.3d (mean) |
(3.3 ± 1.6) per day,up to 9. | Severe group:46(15.1%), non severe group: 259 (84.9%) |
positive rate in severe group vs in non severe group (94.6%vs 82.5%) | NA |
| Xiao [15] | China | Fifth affiliated hospital of Zhuhai | 73 | 26(35.6%) | NA | NA | NA | NA | NA |
| Young [16] | Singapore | Singapore 4 hospitals in Singapore | 18 | 3 (16.6%) | NA | NA | 2 required intensive care | Virus was detectable in the stool (4/8 [50%]) and blood (1/12 [8%]) by PCR | There were no deaths |
| Wan [17] | China | 18 hospitals | 232 | 49(21%) | NA | NA | NA | NA | Diarrhea symptoms were significantly correlated with severe infection of new crown, ventilator use and admission to ICU |
| Wei [18] | China | Wuhan Union Hospital | 84 | 26(31%) | 3.7 days | na | The duration of fever and dyspnea in diarrhea group vs in non diarrhea group(10.5 ± 4.7 vs 7.6 ± 3.4d,8.1 ± 3.2 vs4.7 ± 2.3d). | Stool samples from a higher proportion of patients with diarrhea tested positive for virus RNA (69%) than from patients without diarrhea (17%) | The hospitalization time of diarrhea patients vs non diarrhea ones(16.5 ± 5.2 vs 11.8 ± 5.6d). |
| Luo [19] | China | Zhongnan Hospital of Wuhan University |
183 | 68(37.1%) | NA | NA | NA | NA | NA |
| Liu [20] | China | Affiliated Hospital of Jianghan University | 30 | 9(30%) | NA | NA | NA | NA | NA |
| Pan [21] | China | Wuhan Hanan Hospital; Wuhan Union Hospital; Huanggang Central Hospital |
204 | 35(17.2%) | NA | 3 per day (mean) | NA | NA | Difficult to cure and discharge (34.3% vs 60%) |
| Li [22] | China | 1995 | 96(4.8%) | NA | NA | NA | NA | Fatality rate 5% | |
| Lu [23] | China | Wuhan Children's Hospital | 171 | 15(8.8%) | NA | NA | NA | NA | Two patients death |
| D'Amico [24] | China Singap French Japan United States |
3042 | 292(10,1%) | NA | NA | NA | NA | NA |
NA = no analysis.