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. 2020 Aug 13;2020:5103272. doi: 10.1155/2020/5103272

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Copyright © 2020 Zongyao Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

circ_0026359 was overexpressed in gastric cancer and associated with CDDP resistance and poor survival rates in gastric cancer patients. (a) Expression levels of circ_0026359 in 55 pairs of gastric cancer tissues and normal gastric tissues were examined by RT-qPCR. (b) Expression levels of circ_0026359 in 33 CDDP-sensitive (CS) and 22 CDDP-resistant (CT) gastric cancer tissues. (c) Expression levels of circ_0026359 in normal gastric cell GES-1 and gastric cancer cells HGC-27, AGS, BGC-823, SGC-7901, and MKN-45 were examined by RT-qPCR. (d) Expression levels of circ_0026359 in CDDP-resistant gastric cancer cells SGC-7901/CDDP and MKN-45/CDDP and parental gastric cells SGC-7901 and MKN-45. GAPDH was examined as control for RT-qPCR. (e) Overall survival (OS) rates and (f) relapse-free survival (RFS) rates in gastric cancer patients with high circ_0026359 expression and low circ_0026359 expression were analyzed by Kaplan-Meier curves. ^∗∗P < 0.01; ^∗∗∗P < 0.001.