Table 2.
Performance of KIM-1 for CIN or CI-AKI diagnosis in the meta-analysis.
| Nr. | Author | TP | FP | FN | TN | Total | Test time, hours | AUC | 95% CI | SEN, % | SPE, % | Cutoff, ng/ml | Biological material | Assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wybraniec et al. [22] | 7 | 15 | 2 | 71 | 95 | 6h | 0.0081 | NR | 0.778 | 0.824 | >0.425 | Urine | ELISA |
| 2 | Akdeniz et al. [8] | 24 | 5 | 8 | 15 | 52 | 6 | 0.797 | 0.677–0.917 | 75 | 75 | 3.66 | Urine | ELISA |
| 3 | Li et al. [9] | 14 | 18 | 5 | 108 | 169 | 24 | 0.854 | 0.782–0.929 | 73.7 | 85.7 | 6.327755 | Urine | ELISA |
| 4 | Luo et al. [18] | 10 | 4 | 2 | 26 | 42 | 24 | 0.85 | 0.72–0.95 | 83 | 87 | 0.74 | Urine | ELISA |
| 5 | Torregrosa et al. [19] | 14 | 45 | 6 | 79 | 144 | 12 | 0.713 | 0.551–0.876 | 71.6 | 64 | 1.73 | Urine | ELISA |
| 6 | Wang and Pu [20] | 12 | 8 | 2 | 20 | 42 | 24 | 0.839 | 0.095–0.948 | 85.7 | 71.4 | 4.495 | Urine | ELISA |
| 7 | Wang [21] | 17 | 60 | 3 | 180 | 260 | 12 | 0.903 | 0.802–0.100 | 85 | 75 | 0.0478425 | Urine | ELISA |
| 8 | Wang et al. [10] | 59 | 1 | 3 | 3 | 66 | 12 | 0.742 | NR | 95.2 | 75 | 3∗KIM-1 baseline | Urine | ELISA |
| 9 | Vijayasimha et al. [17] | 11 | 17 | 1 | 71 | 100 | 24 | 0.95 | NR | 89 | 81 | 4.5 | Urine | ELISA |