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. 2020 Aug 20;10(8):e038824. doi: 10.1136/bmjopen-2020-038824

Table 2.

Characteristics according to LVH using ECG and echocardiogram

Characteristics ECG
n=422
ECHO
n=422


P value
LVH+
n=47
LVH−
n=375
P value LVH+
n=184
LVH−
n=238
Demographics
 Age (mean, SD) 70.9±6.4 69.5±6.5 0.166 71.2±6.9 68.5±6.0 <0.001
 Male (n, %) 23 (48.9) 163 (43.5) 0.476 83 (45.1) 103 (43.3) 0.707
 Low education (n, %) 5 (10.6) 48 (12.8) 0.673 24 (13.0) 29 (12.2) 0.792
 Having a partner (n, %) 37 (78.7) 290 (77.3) 0.830 141 (76.6) 186 (78.2) 0.711
Lifestyle
 Current smoker (n, %) 4 (8.5) 50 (13.3) 0.351 19 (10.3) 35 (14.7) 0.182
 Regular alcohol use (n, %)* 14 (29.8) 121 (32.3) 0.731 61 (33.2) 74 (31.1) 0.653
 Recommended physical exercise (n, %)† 8 (17.0) 60 (16.0) 0.858 28 (15.2) 40 (16.8) 0.660
Clinical characteristics and risk factors
 Previous MI (n, %) 2 (4.3) 17 (4.5) 0.931 13 (7.1) 6 (2.5) 0.026
 Peripheral artery disease (n, %) 1 (2.1) 17 (4.5) 0.442 5 (2.7) 13 (5.5) 0.166
 Previous TIA/stroke (n, %) 1 (2.1) 35 (9.3) 0.096 20 (10.9) 16 (6.7) 0.130
 Diabetes (n, %) 4 (8.5) 35 (9.3) 0.854 19 (10.3) 20 (8.4) 0.499
 BMI (mean, SD)‡ 27±4.0 28±4.6 0.178 29±4.3 28±4.7 0.043
 BNP (median, IQR)§ 17 (9.9–31) 9.7 (5.8–16.3) <0.001 11.0 (6.9–18) 9.8 (5.3–17) 0.035
 Total cholesterol (mean, SD)¶ 5.2±1.1 5.1±1.0 0.522 5.1±1.1 5.0±0.9 0.286
 LDL (mean, SD)¶ 3.2±0.9 3.1±0.9 0.746 3.2±0.9 3.1±0.9 0.361
 SBP (mean, SD) 155±23.1 149±19.7 0.041 152±21.7 147±18.7 0.007
 SBP >140 (n, %) 33 (70.2) 248 (66.1) 0.576 128 (69.6) 153 (64.3) 0.254
 SBP >150 (n, %) 28 (59.6) 157 (41.9) 0.021 89 (48.4) 96 (40.3) 0.099
 DBP (mean, SD) 83.7±10.9 81.6±10.7 0.203 81±10.9 82±10.6 0.188
 DBP >90 (n, %) 11 (23.4) 75 (20.0) 0.585 36 (19.6) 50 (21.0) 0.715
 Blood pressure on target (n, %)** 15 (31.9) 160 (42.7) 0.158 71 (38.6) 104 (43.7) 0.291
 Years of hypertension (median, IQR)¶ 10 (4–15) 10 (4–16) 0.629 10 (4–20) 8 (4–15) 0.188

Values for categorical variables are given as number (percentage); values for continuous variables are given as mean±SD or median (IQR). χ2 test for nominal data, t-test for normally distributed continuous data, Mann-Whitney U test for non-normally distributed data. P values <0.05 are in bold.

*Defined as ≥2 glasses of alcohol per day on average.

†Defined as ≥30 min exercise per day, at least 5 days/week.

‡n=418.

§n=400.

¶n=407 due to missing data.

**On-target systolic blood pressure defined as <140 mm Hg for persons aged less than 70 years and <150 mm Hg for persons aged 70 years or more.

BMI, body mass index; BNP, brain natriuretic peptide; DBP, diastolic blood pressure; ECHO, echocardiogram; LDL, low-density lipoprotein; LVH, left ventricular hypertrophy; MI, myocardial infarction; SBP, systolic blood pressure; TIA, transient ischaemic attack.