Table 1.

Time in days from main gold standard diagnosis date to first ever record in each combination of sources

Cancer	NCRAS		NCRAS and HES APC		CPRD GOLD, HES APC and ONS mortality		CPRD GOLD		HES APC
	Median (IQR)	5th–95th percentile	Median (IQR)	5th–95th percentile	Median (IQR)	5th–95th percentile	Median (IQR)	5th–95th percentile	Median (IQR)	5th–95th percentile
Oral cavity (C00-06)	0 (0 to 0)	0–20	0 (0 to 0)	0–12	0 (0 to 17)	0–57	11 (0 to 25)	0–80	12 (0 to 39)	0–91
Oesophageal (C15)	0 (0 to 1)	0–30	0 (0 to 0)	0–6	0 (0 to 0)	0–30	7 (0 to 18)	0–59	0 (0 to 6)	0–85
Stomach (C16)	0 (0 to 2)	0–28	0 (0 to 0)	0–0	0 (0 to 0)	0–37	10 (1 to 22)	0–64	0 (0 to 0)	0–64
Colorectal (C18-C20)*	0 (0 to 3)	0–41	0 (0 to 0)	0–19	0 (0 to 0)	0–36	7 (0 to 21)	0–70	0 (0 to 15)	0–90
Liver (C22)	0 (0 to 7)	0–87	0 (0 to 0)	0–51	0 (0 to 2)	0–72	9 (0 to 29)	0–113	0 (0 to 32)	0–170
Pancreas (C25)	0 (0 to 8)	0–56	0 (0 to 0)	0–23	0 (0 to 0)	0–52	8 (0 to 22)	0–76	0 (0 to 8)	0–101
Lung (C34)*	0 (0 to 5)	0–42	0 (0 to 0)	0–20	0 (0 to 4)	0–56	10 (0 to 22)	0–85	0 (0 to 19)	0–190
Malignant melanoma (C43)	0 (0 to 0)	0–23	0 (0 to 0)	0–29	0 (0 to 21)	0–64	11 (0 to 25)	0–73	31 (0 to 61)	0–240
Breast (C50)*	0 (0 to 0)	0–26	0 (0 to 0)	0–27	7 (0 to 14)	0–37	7 (0 to 14)	0–48	27 (16 to 41)	0–365
Cervix (C53)	0 (0 to 0)	0–17	0 (0 to 0)	0–3	3 (0 to 20)	0–74	13 (4 to 27)	0–79	17 (0 to 48)	0–113
Uterus (C54-55)	0 (0 to 0)	0–19	0 (0 to 0)	0–4	0 (0 to 19)	0–55	14 (7 to 27)	0–69	8 (0 to 41)	0–89
Ovaries (C56)	0 (0 to 3)	0–33	0 (0 to 0)	0–21	0 (0 to 0)	0–41	10 (0 to 24)	0–95	0 (0 to 14)	0–96
Prostate (C61)*	0 (0 to 0)	0–68	0 (0 to 0)	0–82	2 (0 to 22)	0–154	15 (3 to 29)	0–112	65 (0 to 423)	0–2113
Kidney (C64)	0 (0 to 5)	0–66	0 (0 to 0)	0–36	0 (0 to 0)	−24–78	0 (0 to 22)	0–112	0 (0 to 20)	0–250
Bladder (C67)	1 (0 to 15)	0–222	0 (0 to 0)	0–31	0 (0 to 0)	0–29	7 (0 to 30)	0–166	0 (0 to 0)	0–99
Brain/CNS (C71-72)	1 (0 to 8)	0–63	0 (0 to 0)	0–31	0 (0 to 0)	0–32	8 (0 to 20)	0–68	0 (0 to 1)	0–166
Thyroid (C73)	0 (0 to 0)	0–28	0 (0 to 0)	0–20	0 (0 to 25)	0–87	22 (3 to 42)	0–127	1 (0 to 58)	0–154
Non-Hodgkin's lymphoma (C82-85)	0 (0 to 3)	0–43	0 (0 to 0)	0–33	0 (0 to 12)	0–61	16 (4 to 32)	0–118	0 (0 to 31)	0–551
Multiple myeloma (C90)	0 (0 to 8)	0–235	0 (0 to 0)	0–80	0 (0 to 1)	0–75	10 (0 to 28)	0–148	0 (0 to 41)	0–714
Leukaemia (C91-95)	0 (0 to 7)	0–909	0 (0 to 1)	0–1038	0 (0 to 0)	0–89	1 (0 to 20)	0–140	0 (0 to 180)	0–1811

Number of days between main gold standard diagnosis date and applied definitions. Cancer sites are ordered according to corresponding codes from the International Classification of Diseases, version 10 (ICD-10).

*Four most common cancer sites. All sources definition not shown as diagnosis date is the same as the gold standard definition by default.

CNS, central nervous system; CPRD, Clinical Practice Research Datalink; HES APC, Hospital Episode Statistics Admitted Patient Care data; NCRAS, National Cancer Registration and Analysis Service cancerregistration data; ONS, Office for National Statistics.