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. 2020 Aug 23;550:61–69. doi: 10.1016/j.virol.2020.07.015

Table 1.

Best fit parameter estimates for the empirical model.

Untreated animals
Parameter Animal 1 Animal 2 Animal 3 Animal 4 Animal 5
Vp (copies/mL) 3.12×107 7.73×107 1.61×106 2.96×108 5.40×107
95% confidence interval (0.46468.9)×107 (0.85165.5)×107 (0.4496.66)×106 (0.9189.95)×108 (0.731121)×107
tp (d) 1.61 1.33 0.578 1.19 0.582
95% confidence interval 1.23–2.30 1.07–1.68 0.374–1.14 1.06–1.31 0.190–1.02
λg (/d) 11.5 14.2 25.9 17.0 31.8
95% confidence interval 7.13–16.13 10.3–18.2 12.3–39.9 14.9–19.3 19.0–94.2
λd (/d) 2.75 3.18 1.62 2.26 1.49
95% confidence interval 1.97–3.78 2.50–3.90 1.28–2.07 1.92–2.62 0.807–2.15
SSR 6.58 4.76 2.19 1.22 6.55
95% confidence interval 0.718–6.60 0.0700–6.18 0.256–2.85 0.0710–1.55 0.364–9.07
Treated animals
Animal 6 Animal 7 Animal 8 Animal 9 Animal 10
Vp (copies/mL) 1.32×106 3.38×106 6.39×106 4.46×107 8.70×107
95% confidence interval (0.25910.9)×106 (1.1411.5)×106 (0.810147)×106 (1.1817.6)×107 (5.0620.1)×107
tp (d) 1.23 1.04 0.533 1.13 0.999
95% confidence interval 0.460–1.63 0.493–1.19 0.110–1.19 0.573–1.31 0.563–1.10
λg (/d) 12.0 15.1 30.7 16.2 19.0
95% confidence interval 8.03–30.8 13.1–31.5 13.2–166 13.9–30.5 17.3–34.0
λd (/d) 0.457 0.789 0.680 1.66 1.40
95% confidence interval 0.0128–1.08 0.479–1.13 0.0772–1.41 1.25–2.09 1.19–1.62
SSR 3.78 1.15 6.43 1.72 0.520
95% confidence interval 0.423–4.71 0.144–1.20 0.506–9.55 0.123–1.91 0.0579–0.564