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. 2020 Jul 31;96(7):273–296. doi: 10.2183/pjab.96.021

Figure 11.

Figure 11.

L-R asymmetric remodeling of the sixth branchial arch artery in the mouse embryo. In a normal embryo, the right side of the sixth branchial arch artery (BAA) and the right side of the dorsal aorta regress as development proceeds, eventually resulting in arching of the aorta toward the left side. In Pitx2 mutant mice; however, this pattern of remodeling is impaired. AS, aortic sac; RV and LV, right and left ventricle.