Table 2.
Combinations of Aminoglycoside Resistant Determinants and Corresponding MICs for A. Baumannii Strains
| Genes Conferring Aminoglycoside Resistance | Aminoglycosides | Number of Isolates for Which the MIC (µg/mL) Was | Total | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 4 | 16 | 32 | 64 | 128 | 256 | ≥512 | |||
| armA | Amikacin | – | – | – | – | – | – | – | 6 | 34 | 40 |
| Gentamicin | – | – | – | – | – | 8 | – | 7 | 25 | 40 | |
| aphA1 | Amikacin | – | – | – | – | – | – | 9 | 7 | – | 16 |
| Gentamicin | – | – | – | 3 | 1 | 4 | 8 | – | – | 16 | |
| aphA6 | Amikacin | – | – | – | 7 | – | 5 | 51 | 22 | 21 | 106 |
| Gentamicin | – | 3 | 5 | 10 | 10 | 29 | 22 | 7 | 20 | 106 | |
| aacC1 | Amikacin | – | – | – | – | – | 1 | 10 | 12 | – | 23 |
| Gentamicin | – | – | – | – | – | 2 | 21 | – | – | 23 | |
| aadB | Amikacin | – | – | – | 7 | – | 4 | 25 | 22 | 27 | 85 |
| Gentamicin | – | – | – | 5 | 8 | 24 | 23 | 7 | 18 | 85 | |
| armA, aphA6 | Amikacin | – | – | – | – | – | – | – | 6 | 21 | 27 |
| Gentamicin | – | – | – | – | – | – | – | 7 | 20 | 27 | |
| aphA1, aphA6 | Amikacin | – | – | – | – | – | – | 3 | 7 | – | 10 |
| Gentamicin | – | – | – | 1 | – | 2 | 7 | – | – | 10 | |
| aphA1, aacC1 | Amikacin | – | – | – | – | – | – | – | 7 | – | 7 |
| Gentamicin | – | – | – | – | – | – | 7 | – | – | 7 | |
| aphA6, aacC1 | Amikacin | – | – | – | – | – | – | 9 | 12 | – | 21 |
| Gentamicin | – | – | – | – | – | 1 | 20 | – | – | 21 | |
| armA, aadB | Amikacin | – | – | – | – | – | – | – | 6 | 27 | 33 |
| Gentamicin | – | – | – | – | – | 8 | – | 7 | 18 | 33 | |
| aphA1, aadB | Amikacin | – | – | – | – | – | – | – | 7 | – | 7 |
| Gentamicin | – | – | – | – | – | – | 7 | – | – | 7 | |
| aphA6, aadB | Amikacin | – | – | – | 7 | – | 2 | 22 | 22 | 14 | 67 |
| Gentamicin | – | – | – | 4 | 8 | 13 | 22 | 7 | 13 | 67 | |
| aacC1, aadB, | Amikacin | – | – | – | – | – | 1 | 10 | 12 | – | 23 |
| Gentamicin | – | – | – | – | – | 2 | 21 | – | – | 23 | |
| aphA1, aphA6, aacC1, | Amikacin | – | – | – | – | – | – | – | 7 | – | 7 |
| Gentamicin | – | – | – | – | – | – | 7 | – | – | 7 | |
| armA, aphA6, aadB, | Amikacin | – | – | – | – | – | – | – | 6 | 14 | 20 |
| Gentamicin | – | – | – | – | – | – | – | 7 | 13 | 20 | |
| aphA1, aphA6, aadB, | Amikacin | – | – | – | – | – | – | – | 7 | – | 7 |
| Gentamicin | – | – | – | – | – | – | 7 | – | – | 7 | |
| aphA1, aacC1, aadB, | Amikacin | – | – | – | – | – | – | – | 7 | – | 7 |
| Gentamicin | – | – | – | – | – | – | 7 | – | – | 7 | |
| aphA6, aacC1, aadB, | Amikacin | – | – | – | – | – | – | 9 | 12 | – | 21 |
| Gentamicin | – | – | – | – | – | 1 | 20 | – | – | 21 | |
| aphA1, aphA6, aacC1, aadB, | Amikacin | – | – | – | – | – | – | – | 7 | – | 7 |
| Gentamicin | – | – | – | – | – | – | 7 | – | – | 7 | |