Table 3.
Stratification Analyses for rs2272736 Genotypes and Gastric Cancer Survival
| Variable | Case/Death | MST (Month) | HRa (95% CI) | Pa | ||
|---|---|---|---|---|---|---|
| GG/GA | AA | GG/GA | AA | |||
| Tumor site | ||||||
| Cardia | 91/45 | 293/107 | 27 | 31 | 0.68 (0.48–0.97) | 0.032 |
| Non-cardia | 191/76 | 541/191 | 30 | 30 | 0.85 (0.65–1.11) | 0.240 |
| Tumor grade | ||||||
| Well + moderate | 113/41 | 350/100 | 30 | 32 | 0.71 (0.49–1.02) | 0.062 |
| Poor | 163/79 | 474/200 | 29 | 30 | 0.84 (0.65–1.10) | 0.205 |
| TNM classification | ||||||
| Ⅰ + Ⅱ | 98/22 | 327/51 | 31 | 31 | 0.63 (0.38–1.05) | 0.076 |
| III + Ⅳ | 183/100 | 509/250 | 27 | 30 | 0.86 (0.69–1.09) | 0.219 |
| Lauren classification | ||||||
| Intestinal type | 223/88 | 652/201 | 30 | 31 | 0.65 (0.51–0.84) | 0.001 |
| Diffuse type | 60/34 | 188/100 | 27 | 29.5 | 0.92 (0.62–1.37) | 0.675 |
Notes: aAdjusted for age, drinking and smoking status in Cox proportional hazards model. Variable sex was considered as a stratification variable based on the results of proportional hazards tests.
Abbreviations: HR, hazards ratio; CI, confidence interval.