Table 3.
The Characteristics of Inflammatory-Immune Cells in the PCOS and Control Subjects
Parameters | PCOS (N=175) | Control (N=196) | Pd | Poverall | ||||
---|---|---|---|---|---|---|---|---|
Infertility (n=105) | Non-Infertility (n=67) | |||||||
n | Median (Range) | n | Median (Range) | n | Median (Range) | |||
WBC (109/L) | 95 | 6.63 (5.70–7.87) | 63 | 6.41 (5.76–7.94) | 193 | 6.02 (5.07–7.31) | 0.003 | 0.010e,f |
Neu (109/L) | 95 | 3.72 (2.71–4.57) | 63 | 3.74 (2.95–4.87) | 193 | 3.37 (2.59–4.29) | 0.024 | 0.053 |
Lym (109/L) | 98 | 2.19 (1.85–2.64) | 64 | 2.18 (1.83–2.77) | 196 | 2.07 (1.72–2.39) | 0.003 | 0.061 |
T% | 105 | 75.64 (71.65–78.36) | 66 | 73.32 (68.93–77.55) | 196 | 67.28 (62.69–72.69) | <0.001 | <0.001e,f |
CD4+T% | 104 | 41.47 (37.00–44.54) | 65 | 41.51 (37.50–46.88) | 184 | 35.76 (31.85–40.53) | <0.001 | <0.001e,f |
CD8+T% | 104 | 27.57 (24.36–31.22) | 65 | 27.42 (23.87–30.30) | 184 | 26.15 (23.00–30.84) | 0.129 | 0.408 |
CD4/CD8 | 105 | 1.49 (1.21–1.79) | 65 | 1.55 (1.24–1.92) | 184 | 1.39 (1.08–1.72) | 0.007 | 0.015e,f |
B% | 105 | 12.17 (8.37–15.12) | 66 | 11.23 (8.56–14.49) | 196 | 12.33 (10.08–15.20) | 0.107 | 0.264 |
NK% | 103 | 17.67 (13.88–22.28) | 67 | 13.55 (9.50–19.14) | 196 | 12.91 (8.82–17.00) | <0.001 | <0.001e,g |
Notes: Data are shown as median (quarter median- three-fourths median); P<0.05 suggests significantly different. PdSignificant differences between PCOS and Control (P<0.05). PeSignificant differences between Infertility and Control (P<0.05); PfSignificant differences between Non-infertility and Control (P<0.05). PgSignificant differences between Non-infertility and infertility in PCOS (P<0.05).
Abbreviations: WBC, white blood cell; Neu, neutrophil; Lym, lymphocyte; T%, the percentage of T lymphocyte; CD4+T%, the percentage of CD4+T lymphocyte; CD8+T%, the percentage of CD8+T lymphocyte; CD4/CD8, the ratio of CD4/CD8; B%, the percentage of B lymphocyte; NK%, the percentage of natural killer cells (NK cells).