FIGURE 5.

Effects of NGF on the expression of mGlu_1/5 receptors, TRPV1 channels and AKAP5 in cultured DRGs. (a) Changes in the expression of mGlu₁ receptor, mGlu₅ receptor and TRPV1 channel proteins in primary DRG cultures treated with NGF. (b–d) Quantification of mGlu₁ receptor (b), mGlu₅ receptor (c), and TRPV1 channel protein (d), normalized to total β‐actin. (e) Changes in the AKAP5 protein in primary DRG cultures treated with NGF. (f) Quantification of AKAP5 normalized to total β‐actin. Each column and vertical bar represent mean ± SEM (n=5); open circles indicate the individual values. *P < 0.05, significantly different from the NGF‐untreated group; paired t‐test