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. 2020 Jul 20;177(18):4223–4241. doi: 10.1111/bph.15176

FIGURE 6.

FIGURE 6

Effects of NGF on the phosphorylation of TRPV1 and on the interaction between TRPV1 and mGlu1/5 receptors in cultured DRGs. (a) Changes in the phosphorylation of TRPV1 at S800 in DRG cultures treated with NGF. Samples were immunoprecipitated with anti‐TRPV1 antibody. (b) Quantification of phosphorylated TRPV1 normalized to total TRPV1. (c) Changes in the interaction of mGlu1/5 receptors and TRPV1 channels in DRG cultures treated with NGF. Samples were immunoprecipitated with anti‐TRPV1 antibody. (d) Quantification of mGlu5 receptor protein normalized to total TRPV1 channel protein. Each column and vertical bar represent mean ± SEM (n =5); open circles indicate the individual values. *P < 0.05, significantly different from the NGF‐untreated group; paired t‐test