Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for Acinar Cell Zonation in db/db Mice
Islet cells elevate CCK levels (green dots), which elicit a zonated increase in both the expression of trypsin genes in peri-islet acinar cells and their basal secretion (blue dots). Such induction could contribute to islet capsule ECM remodeling, potentially facilitating islet expansion (red arrows).
