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. 2020 Aug 24;24:518. doi: 10.1186/s13054-020-03241-6

Table 4.

Mortality associated with infection site and pathogen

Overall TPE No TPE p
Site of infection
 Pneumonia 26/40 (65%) 11/23 (47.8%) 15/17 (88.2%) 0.017
 GU 2/14 (14.3%) 0/6 (0%) 2/8 (25%)
 GI/biliary 6/12 (50%) 2/6 (33.3%) 4/6 (66.7%)
 Skin/soft tissue 1/5 (20%) 1/1 (100%) 0/4 (0%)
 Endocarditis 2/4 (50%) 1/3 (33.3%) 1/1 (100%)
 Primary bacteremia 5/5 (100%) 1/1 (100%) 4/4 (100%)
Organism cultured
 MRSA 2/5 (40%) 1/3 (33.3%) 1/2 (50%)
Streptococcus 3/5 (60%) 1/2 (50%) 2/3 (66.7%)
E. coli 6/11 (54.5%) 2/5 (40%) 4/6 (66.7%)
Pseudomonas 2/2 (100%) 1/1 (100%) 1/1 (100%)
Enterococcus 1/2 (50%) 0/1 (0%) 1/1 (100%)
Enterobacter 3/8 (37.5%) 2/3 (66.7%) 1/5 (20%)
Klebsiella 2/6 (33.3%) 0/4 (0%) 2/2 (100%)
 Influenza 2/3 (66.7%) 0/1 (0%) 2/2 (100%)
Serratia 1/1 (100%) 1/1 (100%) n/a
C. difficile 1/2 (50%) n/a 1/2 (50%)
Salmonella 0/1 (0%) n/a 0/1 (0%)
 Culture negative 3/14 (21.4%) 1/10 (10%) 2/4 (50%)
 Polymicrobial 16/20 (80%) 7/9 (77.8%) 9/11 (81.8%)

*Pathogens in polymicrobial infections are not specified in the numbers above