Table 6.

Effect of TPE on lactate and platelets with associated mortality

Measure	Survivors	Non-survivors	p
Platelet nadir, TPE (× 1000/μL)	58.1	37.2	0.076
Platelet nadir, control (× 1000/μL)	83.8	68.2	0.27
Platelet recovery, TPEa	23/25 (92%)	2/25 (8%)	0.0001
Lack of platelet recovery, TPEa	1/15 (6.7%)	14/15 (93.3%)
Platelet recovery, controla	13/19 (68.4%)	6/19 (31.6%)	0.0003
Lack of platelet recovery, controla	1/16 (6.2%)	15/16 (93.8%)
24 h lactate levels, TPE	2.9	7.2	0.048
24 h lactate levels, control	4.4	8.2	0.05

^aRecovery to > 100 × 10³/μL; note: five control patients died prior to developing platelet count < 100 × 10³/μL