Table 1.
Patients, tumours and treatment, n (%)
| All, n = 102 | MMC, n = 34 | Oxaliplatin/5-FU, n = 68 | P value1 | |
| Male sex | 60 (59) | 24 (40) | 36 (60) | 0.135 |
| Age in yr, median (range) | 57.2 (23-80) | 56.3 (23-73) | 57.7 (40-80) | 0.884 |
| BMI in kg/m² | 25.3 (15.9-39.6) | 25.5 (19.1-33.6) | 25.2 (15.9-39.6) | 0.266 |
| ASA-score | 0.002b | |||
| 1-2 | 49 (48) | 24 (71) | 25 (37) | |
| 3-4 | 53 (52) | 10 (29) | 43 (63) | |
| Tumour location | 1.000 | |||
| Colon | 91 (89) | 30 (88) | 61 (90) | |
| Rectum | 11 (11) | 4 (12) | 7 (10) | |
| Surgical approach | 0.257 | |||
| Complete cytoreduction | 99 (97) | 32 (94) | 67 (99) | |
| Palliative resection | 3 (3) | 2 (6) | 1 (2) | |
| Resection | ||||
| Peritoneum | 81 (80) | 29 (85) | 52 (77) | 0.437 |
| Omentum | 66 (65) | 26 (77) | 40 (59) | 0.123 |
| Colon/rectum | 55 (54) | 18 (53) | 37 (54) | 1.000 |
| Small intestine | 49 (48) | 15 (44) | 34 (50) | 0.675 |
| Liver | 42 (41) | 13 (38) | 29 (43) | 0.831 |
| Diaphragm | 16 (16) | 9 (27) | 7 (10) | 0.045a |
| Other | 63 (64) | 21 (68) | 42 (62) | 0.655 |
| Pretherapeutic T stage | 0.027a | |||
| T1 | 2 (2) | 0 | 2 (3) | |
| T2 | 2 (2) | 0 | 2 (3) | |
| T3 | 34 (34) | 13 (41) | 21 (31) | |
| T4a | 40 (40) | 17 (53) | 23 (34) | |
| T4b | 22 (22) | 2 (6) | 20 (30) | |
| Pretherapeutic N stage | 1.000 | |||
| N0 | 26 (26) | 8 (25) | 18 (27) | |
| N+ | 73 (74) | 24 (75) | 49 (73) | |
| Pretherapeutic M stage | 1.000 | |||
| M0 | 36 (37) | 12 (35) | 24 (38) | |
| M+ | 62 (63) | 22 (65) | 40 (63) | |
| Tumour grading | 1.000 | |||
| G1 | 0 | 0 | 0 | |
| G2 | 59 (63) | 22 (65) | 37 (63) | |
| G3 | 34 (37) | 12 (35) | 22 (37) | |
| PCI score (0-39) | 9.4 (0-39) | 12.0 (0-39) | 8.1 (0-30) | 0.312 |
| Postop CC-level | 0.350 | |||
| CC0 | 89 (87) | 28 (82) | 61 (90) | |
| CC1 | 8 (8) | 3 (9) | 5 (7) | |
| CC2/3 | 5 (5) | 3 (9) | 2 (3) | |
| Mucinous cells | 21 (21) | 6 (18) | 15 (22) | 0.796 |
1
Fisher's exact test.
a
P < 0.05.
b
P < 0.01. 5-FU: 5-Fluorouracil; ASA: American Society of Anesthesiologists; BMI: Body mass index; MMC: Mitomycin C; PCI: Peritoneal cancer index.