Table 3.
Predictor | n | Median survival in mo | P value1 |
Sex | 0.884 | ||
Male | 60 | 49 | |
Female | 42 | 57 | |
Age | 0.147 | ||
< 50 yr | 27 | 38 | |
≥ 50 yr | 75 | 49 | |
Preoperative BMI | 0.423 | ||
< 18.5 | 4 | 4 | |
18.5-25 | 49 | 53 | |
25-30 | 35 | 51 | |
> 30 | 14 | 49 | |
ASA score | 0.457 | ||
1-2 | 49 | 49 | |
3-4 | 53 | 57 | |
Primary tumour location | 0.620 | ||
Colon | 91 | 49 | |
Rectum | 11 | 23 | |
Primary T-stage | 0.669 | ||
T1-3 | 38 | 49 | |
T4a | 40 | 30 | |
T4b | 22 | Not reached | |
Primary nodal stage | 0.013a | ||
N0 | 26 | 88 | |
N1 | 31 | 51 | |
N2a | 19 | 30 | |
N2b | 23 | 18 | |
Primary distant metastasis | 0.046a | ||
M0 | 36 | 57 | |
M+ | 62 | 35 | |
Primary tumour grading | 0.010a | ||
G2 | 59 | 51 | |
G3 | 34 | 29 | |
Primary tumour resection | 0.035a | ||
R0 | 76 | 51 | |
R1 | 20 | 30 | |
R2 | 4 | 16 | |
Cytoreduction level | < 0.001b | ||
CC0 | 89 | 49 | |
CC1 | 10 | 12 | |
CC2-3 + palliative resections | 3 | 3 | |
PCI-score | < 0.001b | ||
< 10 | 56 | 51 | |
10-20 | 29 | 27 | |
20-30 | 11 | 10 | |
> 30 | 5 | 9 | |
Operation extent | |||
Partial colectomy | 55 | 53 | 0.189 |
No colon resection | 47 | 31 | |
Small bowel resection | 49 | 30 | 0.355 |
No small bowel resection | 53 | 51 | |
Liver metastasis resection | 42 | 27 | 0.024a |
No liver resection | 60 | 51 | |
HIPEC regimen | 0.139 | ||
MMC | 34 | 30 | |
Oxaliplatin/5-FU | 68 | Not reached |
Univariate analysis by Kaplan-Meier method with log-rank test for the comparison of subgroups.
P < 0.05.
P < 0.01. 5-FU: 5-Fluorouracil; ASA: American Society of Anesthesiologists; BMI: Body mass index; HIPEC: Hyperthermic intraperitoneal chemotherapy; MMC: Mitomycin C; PCI: Peritoneal cancer index.