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. 2020 Jul 29;117(33):20139–20148. doi: 10.1073/pnas.2007474117

Fig. 5.

Fig. 5.

Inducible expression of ErbB2ΔEx16 drives lung adenocarcinoma. (A) Schematic diagram illustrating the ERBB2ΔEx16-IRES-GFP/CCSP-rtTA cross. (B) H&E staining (Top) and ERBB2 immunohistochemistry (Bottom) were performed on lung tissue sections from ERBB2ΔEx16/CCSP-rtTA mice at the indicated time points following DOX administration. (Scale bar: 200 μm.) (C) H&E staining (Top Panels) and ERBB2 immunohistochemistry (Bottom) were performed on lung tissue sections from ERBB2-FL/CCSP-rtTA and ERBB2ΔEx16/CCSP-rtTA mice at the indicated time points following DOX administration. (Scale bar: 100 μm.)