Fig. 5.

Inactivation of MTR increases mitochondrial fission. (A) Viability of wild-type (WT) and drp-1(lf) grown on indicated RNAi clones. Mean ± SD from at least three biological replicates. n = 90∼120 for each data point. **P < 0.01. (B) Mitochondrial morphologies and lengths in body wall muscles in wild-type, lmp-1(lf) and drp-1(lf) grown on indicated RNAi clones. Arrows indicate some examples of nice parallel mitochondrial structure. Mitochondrial lengths were calculated by MiNA toolset. Median with 95% CI Mann–Whitney U test. ****P < 0.0001. N indicates the sample size. (Scale bar, 5 μm.)