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. 2020 Aug 3;117(33):20052–20062. doi: 10.1073/pnas.2004524117

Fig. 1.

Fig. 1.

Early adversity has negative effects on adult health outcomes in many species, including humans (solid arrow). However, early adversity is also frequently associated with social dysfunction (e.g., greater isolation or less supportive relationships) across the life course, which may itself contribute to negative health outcomes. The dashed arrows represent the proposed mediating effect of weak social bonds on the relationship between early adversity and adult health.