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Dependence of SIR on the quantitative relationship between m.o.i. of 1st-INF and 2nd-INF. (a) Integration events per cell were estimated from cells which were (i) single infection with the indicated HIV-1 or (ii) 1st-INF with INm HIV-1 (m.o.i.=1) and then 2nd-INF with the indicated ΔRev virus (m.o.i.=1 or 10). (a, ii) Inset, magnification of the marked section. (b) m.o.i. titration of ΔRev HIV-1 at 20 h post-1st-INF with INm HIV-1.
