Table 2.
Laboratory, hemodynamic, and echocardiographic parameters of all participants.
| Variable | IPAH with desaturation (n = 17) | IPAH without desaturation (n = 33) | P value |
|---|---|---|---|
| Laboratory parameters | |||
| NT-pro BNP (pg · mL−1) | 1244.29 ± 2298.35 | 987.86 ± 1182.94 | 0.466 |
| CRP (mg · L−1) | 4.42 ± 2.93 | 3.84 ± 4.79 | 0.762 |
| Hs-CRP (mg · L−1) | 3.13 ± 3.38 | 2.40 ± 3.03 | 0.57 |
| RHC parameters | |||
| MRAP (mmHg) | 10.00 ± 6.81 | 5.06 ± 3.18 | 0.007 |
| MRVP (mmHg) | 12.29 ± 5.47 | 9.15 ± 5.50 | 0.179 |
| SPAP (mmHg) | 98.43 ± 24.17 | 121.42 ± 180.87 | 0.741 |
| DPAP (mmHg) | 45.29 ± 7.65 | 39.55 ± 15.85 | 0.359 |
| MPAP (mmHg) | 62.14 ± 14.24 | 56.57 ± 20.99 | 0.509 |
| PCWP (mmHg) | 9.17 ± 3.66 | 7.80 ± 3.88 | 0.433 |
| Qp (L/min) | 3.63 ± 1.06 | 4.25 ± 0.98 | 0.144 |
| Qs (L/min) | 3.77 ± 1.06 | 4.82 ± 1.34 | 0.063 |
| CI (L · min−1 · m−2) | 2.37 ± 0.57 | 2.99 ± 0.79 | 0.538 |
| PVR (dyn · s · cm−5) | 1537.87 ± 691.27 | 1144.02 ± 508.97 | 0.09 |
| Echocardiographic parameters | |||
| Left ventricular ejection fraction | 66.00 ± 4.93 | 62.53 ± 4.41 | 0.071 |
| Diastolic left auricle diameter (mm) | 30.29 ± 3.86 | 28.64 ± 3.00 | 0.216 |
| Diastolic left ventricle diameter (mm) | 35.29 ± 5.38 | 36.21 ± 6.17 | 0.715 |
| Diastolic right ventricle diameter (mm) | 32.57 ± 8.44 | 31.70 ± 5.59 | 0.734 |
| VTR (m/s) | 3.92 ± 0.75 | 17.07 ± 73.87 | 0.669 |
| PTR (mmHg) | 58.07 ± 32.44 | 71.81 ± 28.90 | 0.299 |
Note: Data are presented as mean ± SD or median (interquartile range).
IPAH: idiopathic pulmonary arterial hypertension; NT-pro BNP: N-terminal pro-brain natriuretic peptide; CRP: C reactive protein; Hs-CRP: high sensitive C reactive protein; RHC: right heart catheterization; MRAP: mean right atrium pressure; MPAP: mean pulmonary arterial pressure; SPAP: systolic pulmonary artery pressure; CI: cardiac index; PVR: pulmonary vascular resistance; VTR: the speed of tricuspid regurgitation; PTR: the pressure difference of tricuspid regurgitation.