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. Author manuscript; available in PMC: 2020 Aug 24.
Published in final edited form as: Cancer Cell. 2018 Dec 10;34(6):996–1011.e8. doi: 10.1016/j.ccell.2018.10.016

KEY RESOURCES TABLE

REAGENT or RESOURCE SOURCE IDENTIFIER
Antibodies
Anti-ESRP1 rabbit polyclonal antibody Sigma Aldrich, Germany Altas antibody Cat# HPA023720, AB_1856125
Anti- CD45 antibody BioLegend, US AB_1236444
Anti- CD326 antibody BioLegend, US AB_400261
Anti- CD271 antibody BioLegend, US AB_2282827
Anti- CD26 antibody BioLegend, US AB_10913814
Anti- CD31 antibody BioLegend, US AB_2562179
Biological Samples
Primary and metastasis tumor samples and normal samples This paper
Critical Commercial Assays
Qiagen AllPrep DNA/RNA/Protein Mini Kit
EnVision Kit Dako, Glostrup, Denmark Cat#K4003
RNA6000 nano assays Agilent Cat#5065-4401
RNA Fragmentation Reagents Ambion Cat#AM8740
Deposited Data
Raw sequencing data This paper EGAS00001002923
Somatic variants This paper doi:10.17632/6gtrrxrn2c.1
Software and Algorithms
R-3.4 R Core Team 2017 https://www.R-project.org
randomForestSRC 2.5.1 Ishwaran et al., 2008 https://cran.r-project.org/package=randomForestSRC
YAPSA Huebschmann et al, 2016 https://bioconductor.org/packages/YAPSA/
SAMtools Li et al., 2009 http://www.htslib.org/
Freebayes v1.1.0 Garrison et al., 2012 https://github.com/ekg/freebayes
Sequenza v2.2.0.9000 Favero et al., 2015 https://bitbucket.org/sequenza_tools/sequenza_canopy)
CLICK algorithm Sharan et al., 2003 http://acgt.cs.tau.ac.il/expander/
Canopy 1.1.1 Jiang et al., 2016 https://CRAN.R-project.org/package=Canopy
PEPCI This paper http://computational-epigenomics.com/downloads/PEPCI.R
DKFZ SNV pipeline https://doi.org/10.1101/161638
BWA-MEM Li, 2013 http://bio-bwa.sourceforge.net/
PCAWG delly workflow Rausch et al., 2012 https://github.com/ICGC-TCGA-PanCancer/pcawg_delly_workflow
LUMP algorithm Aran et al, 2015 www.ncbi.nlm.nih.gov/pubmed/26634437
RnBeads Assenov et al., 2014 https://bioconductor.org/packages/RnBeads/
EpiAnnotator Pageaud et al., 2018 http://epigenomics.dkfz.de/EpiAnnotator/
NNLS algorithm https://cran.r-project.org/web/packages/nnls
Houseman algorithm Houseman et al., 2012 www.ncbi.nlm.nih.gov/pubmed/22568884
edgeR Mortazavi et al., 2008; Robinson and Oshlack, 2010 http://bioconductor.org/packages/edgeR/
Genomatix software(v3.80116) http://www.genomatix.de/
PRESCIENT This paper https://bitbucket.org/weischenfeldt/prescient
R package survminer v0.3.1 https://cran.r-project.org/web/packages/survminer/index.html
R package survival v2.41-3 Therneau and Grambsch, 2000 https://cran.r-project.org/web/packages/survival/index.html
Cytoscape v3.4.0 http://www.cytoscape.org/
Other
Cancer Genome Interpreter drug-variant list Tamborero et al, 2018 https://www.cancergenomeinterpreter.org/data/cgi_biomarkers_latest.zip
H3K27me3, H3K27Ac, H3K4me1, and H3K4me3 ChIP data from LNCaP cells Barfeld et al. 2017 https://www.ncbi.nlm.nih.gov/m/pubmed/28412251/
Phospho S5 RNA Pol II ChIP data Massie et al. 2011 https://www.ncbi.nlm.nih.gov/pubmed/21602788
H3K27me3, H3K4me1, H3K27me3 ChIP data from VCaP cells Yu et al. 2010 https://www.ncbi.nlm.nih.gov/pubmed/20478527
RNA pol II ChIP data from VCaP cells Asangani et al. 2014 https://www.ncbi.nlm.nih.gov/pubmed/24759320
Ensembl Variant Effect Predictor (VEP) https://www.ensembl.org/info/docs/tools/vep/index.html
Exome Aggregation Consortium(ExAC) http://exac.broadinstitute.org
IARC TP53 database http://p53.iarc.fr/
ClinVar https://www.ncbi.nlm.nih.gov/clinvar/
1000 Genomes Project http://www.internationalgenome.org
NHLBI GO Exome Sequencing Project https://esp.gs.washington.edu/drupal/
COSMIC database http://cancer.sanger.ac.uk/cosmic/signatures
TCGA-PRAD RNA seq (Downloaded: 05 April 2017) https://portal.gdc.cancer.gov/
TCGA-PRAD Level 3 SNP-array segmentation (Downloaded: 25 June 2018) https://portal.gdc.cancer.gov/