Fig. 3.

CircSIPA1L1 sponges miR-617. a RT-PCR assay showed the transfection efficacy of NC, miR-617 mimics, miR-617 inhibitor, and inhibitor NC group. b Relative circSIPA1L1 expression level in DPSCs transfected with miR-617 mimics or inhibitor (**P < 0.01). c, d FISH showed co-localization of circSIPA1L1 and miR-617 in the cytoplasm of DPSCs cells (arrow). U6 and 18S were the internal control. e The potential binding sequences in 3′UTR of circSIPA1L1 and miR-617 predicted online. f Luciferase activity in 293T cells co-transfected with miR-617 mimics/NC and wild-type/mutant-type circSIPA1L1, respectively. *P < 0.05, **P < 0.01