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. 2020 May 4;29:0963689720903691. doi: 10.1177/0963689720903691

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 5. — Evaluation of islet function in vivo of TNF-α-treated islets that were isolated with or without CORM-2 pretreatment. (A, B) Results of blood glucose (A) and body weight (B) measurements (n = 8). (C) Blood glucose levels of mice in IPGTT on day 14. (D) Area under the curve of blood glucose levels of mice in IPGTT on day 14. Data are shown as mean ± SD. ^a P < 0.05: control group vs control + TNF-α group; ^b P < 0.05: CORM-2 + TNF-α treatment group vs control + TNF-α group (one- (D) or two-way (C) ANOVA with post hoc Tukey’s test). CORM-2: carbon monoxide-releasing molecule 2; IPGTT: intraperitoneal glucose tolerance test; TNF-α: tumor necrosis factor-α.