FIGURE 5.

CCL7 is expressed in human kidneys during AKI. (A) Deconvolution analysis of B cell, neutrophil, and monocyte enrichment from biopsy specimen–confirmed healthy and AKI kidneys of previously published dataset (n = 39 humans in total); a nonparametric Mann–Whitney U test was used. (B) CCL7 transcript from the same dataset. (C) Receiver-operating characteristic curve of CCL7 transcripts as a classifier of AKI from the same dataset. (D) CCL7 qPCR of lysate from snap-frozen kidney cortex from donors with and without preterminal AKI (n = 15 humans in total); a parametric unpaired t test was used. (E) ELISA measurements of CCL7 in urine from patients with and without AKI (n = 49 humans in total); a parametric unpaired t test was used. *p < 0.05, **p < 0.01.