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Effect of puerarin on DDP-induced Numb/Notch1 signaling pathway. (A and B) Reverse transcription-quantitative PCR and (C and D) western blot analysis was performed to determine the expression levels of Numb and Notch1 in HK-2 cells. Data are presented as the mean ± standard deviation. n=3. *P<0.05 vs. sham; #P<0.05 vs. DDP treatment or DDP+NC inhibitor. DDP, cisplatin; Pue, puerarin; NC, negative control.
