Table I.
Published data of KATs.
| Author, year | KAT family | Members | Localization | Substrate | (Refs.) |
|---|---|---|---|---|---|
| Fournier et al, 2016 | GNAT | GCN5 (KAT2A) | Nucleus | PLK4 and TBX5 | (34) |
| Ghosh et al, 2018 | PCAF (KAT2B) | (36) | |||
| Ruiz-Garcia et al, 1998 | HAT1 | Cytoplasm/ | Histone | (23) | |
| nucleus | |||||
| Miskiewicz et al, 2011 | ELP3 | Cytoplasm/nucleus | Brunchpilot | (24) | |
| Sampath et al, 2013 | HPA2 | Cytoplasm | Histone/Polyamines/Small basic proteins | (25) | |
| HPA3 | Cytoplasm | Histone/Polyamines/D-amino acids | |||
| Bao et al, 2018 | MYST | (35) | |||
| Cheng et al, 2019 | Tip60 (KAT5) | Nucleus | Ran and Pacer | (37) | |
| Rokudai et al, 2013 | MOZ (KAT6A) | Nucleus | p53 | (33) | |
| Pelletier et al, 2002 | MORF (KAT6B) | Nucleus | Runx2 | (32) | |
| Miotto et al, 2002 | HBO1 (KAT7) | Nucleus | CDT1 | (38) | |
| Yuan et al, 2012 | MOF (KAT8) | Nucleus | Histone | (39) | |
| Reiter et al, 2015 | SAS2 | Nucleus | Histone | (27) | |
| Church et al, 2017 | SAS3 | Nucleus | Histone | (28) | |
| Yan et al, 2000 | ESA1 | Nucleus | Histone | (29) | |
| Chang et al, 2017 | p300/CBP | p300 (KAT3B) | Nucleus | Snail/Smad4/PCNA/ | (40) |
| Yang et al, 2015 | FoxO1 | (41) | |||
| Cazzalini et al, 2014 | (42) | ||||
| Senf et al, 2011 | CBP (KAT3A) | Nucleus | Snail/FoxO1/PCNA | (43) | |
| Lee et al, 2018 | TAFII230/250 | TAFII250 | Nucleus | Histone | (44) |
| Nakakura et al, 2016 | Others | ATAT1 | Cytoplasm | α-tubulin | (45) |
| Zhang et al, 2008 | ESCO1 | Nucleus | SMC3 | (46) | |
| ESCO2 | Nucleus | ||||
| Wu et al, 2012 | HAT1 (KAT1) | Nucleus | Histone | (47) |
GNAT, GCN5-related N-acetyltransferases family; GCN5, general control of amino acid synthesis protein 5; PCAF, p300/CBP-associated factor; Tip60, 60 kDa tat-interactive protein; MOZ, monocytic leukemia zinc finger protein; MORF, MOZ-related factor; HBO1, histone acetyltransferase binding to ORC1; MOF, ortholog of Drosophila males-absent on the first; CBP, CREB-binding protein; TAFII250, transcription initiation factor TFIID 250 kDa subunit; ATAT1, α-tubulin N-acetyltransferase 1; PLK4, polo-like kinase 4; TBX5, T-box protein 5; Runx2, runt-related transcription factor 2; CDT1, chromatin licensing and DNA replication factor 1; PCNA, proliferating cell nuclear antigen; ESCO, establishment of sister chromatid cohesion N-acetyltransferase; HAT1, histone acetyltransferase 1; Ran, ras-related nuclear protein; Snail, zinc finger protein SNAI1; FoxO1, forkhead box protein O1; SMC3, structural maintenance of chromosomes 3; ELP3, elongator complex protein 3; HPA2, histone acetyltransferase HPA2; SAS2, histone acetyltransferase SAS2; ESA1, Histone acetyltransferase ESA1.