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. 2020 Aug 5;20(4):3733–3739. doi: 10.3892/etm.2020.9097

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of PSPs on the TLR4/NF-κB pathway in lung tissue of ALI rats. (A) Western blot analysis was used to detect the expression of proteins in lung tissues of the different group of rats: control group, LPS group and H-PSP group. (B) Statistical analysis of the western blotting. A total of 10 rats in each group, each indicator for each rat was tested at least 3 times independently; ^***P<0.001 vs. the control group; ^##P<0.01 and ^###P<0.001 vs. the LPS group. PSPs, Polygonatum sibiricum polysaccharides; TLR4, Toll-like receptor 4; NF-κB, nuclear factor-κB; ALI, acute lung injury; LPS, lipopolysaccharide. Groups: L-PSP, 20 mg/kg; M-PSP, 40 mg/kg; H-PSP, 80 mg/kg PSPs.