Table 3.

Subcutaneous dosing regimen for venous thromboprophylaxis in pregnancy and the postpartum interval

(This table is adapted from RCOG Green-top Guidelines No. 37a. Reducing risk of thrombosis and embolism in pregnancy and the puerperium [31])

Booking weight** (kg)	Dalteparin (first line)	Enoxaparin (second line)
< 50 kg	2500 units daily	20 mg daily
50–90	5000 units daily	40 mg daily
91–130	7500 units daily*	60 mg daily*
131–170	10,000 units daily*	80 mg daily*
> 170	75 units/kg/day*	0.6 mg/kg/day*
High prophylactic (intermediate) dose for women weighing 50–90 kg	5000 units twice daily	40 mg twice daily
Therapeutic/treatment dose	100 units/kg twice daily antenatally 200 units/kg daily postnatally	1 mg/kg twice daily antenatally 1.5 mg/kg daily postnatally

*May be given in two divided doses

**LMWH should be given in doses titrated against the woman’s booking weight. Women should be re-weighed if there appears to be a significant discrepancy between booking weight and current appearance