Table 1. Impact of immune response on DENV2, ZIKV and CHIKV infection in salivary glands.
| Pathway | Gene | Virus | Induced1 Log2(fold-change) | Function2 | |||
|---|---|---|---|---|---|---|---|
| Proviral | Antiviral | ||||||
| Dissemination | Replication | Dissemination | Replication | ||||
| Toll | CLIPB13A (AAEL003243) | DENV2 | |||||
| ZIKV | 0.7055 | ||||||
| CHIKV | 0.6353 | ||||||
| CLIPB21 (AAEL001084) | DENV2 | ||||||
| ZIKV | 1.3290 | ||||||
| CHIKV | 1.0705 | ||||||
| Est-like (AAEL012775) | DENV2 | ||||||
| ZIKV | |||||||
| CHIKV | 1.1382 | ||||||
| Snk-like (AAEL002273) | DENV2 | 1.5291 | |||||
| ZIKV | |||||||
| CHIKV | 2.4517 | ||||||
| IMD | IKK2 (AAEL012510) | DENV2 | |||||
| ZIKV | |||||||
| CHIKV | 0.6699 | ||||||
| Ect4 (AAEL014931) | DENV2 | ||||||
| ZIKV | |||||||
| CHIKV | 0.4973 | ||||||
| JNK | Kayak (AAEL008953) | DENV2 | |||||
| ZIKV | |||||||
| CHIKV | 0.5394 | ||||||
| Putative immune | JHI (AAEL000515) | DENV2 | 1.3759 | ||||
| ZIKV | 0.7269 | ||||||
| CHIKV | 0.8029 | ||||||
|
Gale5 (AAEL003844) |
DENV2 | 0.6647 | |||||
| ZIKV | |||||||
| CHIKV | 1.4059 | ||||||
1Induction in SGs as measured with RNA-seq.
2Determined by RNAi-mediated silencing studies in SGs.