Table 2. Pathogen specific essential cytoplasmic proteins as novel therapeutic targets.

Sl. No	Protein Id	KO assignment	Description	Pathways
1	Q87L83	K09823	Fur family transcriptional regulator, zinc uptake regulator	Quorum sensing
2	Q87GW9	K07674	Two-component system, narl family, nitrate/nitrite sensor histidine kinase narq	Two-component system
3	Q79YW1	K02410	Flagellar motor switch protein flig	Bacterial chemotaxis
4	Q87HD9	K11904	Type VI secretion system secreted protein vgrg	Bacterial secretion system
5	Q87TC9	K02461	General secretion pathway protein L	Bacterial secretion system
6	Q87NV3	K07780	Arac family transcriptional regulator required for anaerobic and stationary phase induction of genes	Two-component system
7	Q87K78	K07718	Two-component system, sensor histidine kinase yesm	Two-component system
8	Q87I65	K07688	Two-component system, narl family, response regulator, fimbrial Z protein, fimz	Two-component system
9	Q87TD5	K02455	General secretion pathway protein F	Biofilm formation
10	Q87MI1	K03567	Glycine cleavage system transcriptional repressor	Biofilm formation
11	Q87HC5	K11892	Type VI secretion system protein impk	Bacterial secretion system
12	Q87Q12	K02053	Putative spermidine/putrescine transport system permease protein	Quorum sensing
13	Q87LE2	K03092	RNA polymerase sigma-54 factor	Biofilm formation
14	Q87HC6	K11891	Type VI secretion system protein impl	Biofilm formation
15	Q79YX4	K03408	Purine-binding chemotaxis protein chew	Bacterial chemotaxis
16	Q87NG0	K11617	Two-component system, narl family, sensor histidine kinase lias	Two-component system