Figure 3. . CIPN8 score by cumulative dose (cumulative dose * T_{c >0.05}) stratified by whether a patient carried 0 (red line), 1 (green line) or 2 (blue line) FZD3 tag SNV rs7833751 alleles.

Peripheral neuropathy sensitivity was decreased for each rs7833751 variant allele a patient carried (β-coefficient = -0.41; 95% CI: -0.66 to -0.17; p = 0.0011). Thick lines represent lines of best fit.