Table III.
Pooled associations between intratumoral TIL subsets and overall survial of patients with gastric cancer
| Subsets | No. of studies | No. of patients | Analysis model | HR (95% CI) | P-value | Heterogeneity I2, p | Publication bias Begg’s p, Egger’s p |
|---|---|---|---|---|---|---|---|
| CD8+ TIL | 7 | 1630 | Fixed | 0.699 (0.625–0.782) | < 0.001 | 4.3%, 0.394 | 0.368, 0.825 |
| CD4+ TIL | 5 | 1211 | Fixed | 0.770 (0.673–0.881) | < 0.001 | 47.5%, 0.107 | 0.806, 0.578 |
| CD3+ TIL | 7 | 1812 | Fixed | 0.610 (0.526–0.708) | < 0.001 | 0.0%, 0.926 | 0.230, 0.391 |
| FOXP3+ TIL | 9 | 1793 | Random | 1.382 (0.944–2.025) | 0.096 | 77.4%, < 0.001 | 0.466, 0.080 |